The old Inca capital

Food
Cusco
After a 'free' walk

Cusco is perhaps the prime tourist destination on the continent, and feels that way. To the town's credit, they handle all the attention reasonably well, at the cost of moving with the times, the town's main square seeing branches of KFC, McDonald's and Starbucks.

Visiting nearby Machu Picchu is almost prohibitively expensive, and something that still suffers from bureaucratic challenges. There is a limited number of tickets available per day and you have to buy them through official outlets. Online there's only one, and it only accepts Visa.
Entrance to Machu Picchu is about 50USD. Getting there is either by train or walking. The four day hike costs several hundred dollars, the train ride starts at about 100 dollars, for a round trip and can be, literally, ten times as much. But, not only Machu Picchu itself, also the journey to get there passes by sights of mesmerizing beauty.

Cusco is a town of pretty colonial beauty. Before the Spaniards took over and tried to wipe out want went before, it was where the Inca empire had their nominal capital. Some of the streets are pre-Colombian and quite a few of the buildings in downtown Cusco have parts of their walls constructed from the constructions that were standing when the Spaniards showed up.

Surprisingly, tuctucs are not an uncommon sight.

Related:  For the food